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PaSD-qc: quality control for single cell whole-genome sequencing data using power spectral density estimation

Single cell whole-genome sequencing (scWGS) is providing novel insights into the nature of genetic heterogeneity in normal and diseased cells. However, the whole-genome amplification process required for scWGS introduces biases into the resulting sequencing that can confound downstream analysis. Her...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Sherman, Maxwell A, Barton, Alison R, Lodato, Michael A, Vitzthum, Carl, Coulter, Michael E, Walsh, Christopher A, Park, Peter J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5829578/
https://ncbi.nlm.nih.gov/pubmed/29186545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1195
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