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Compensation for chronic oxidative stress in ALADIN null mice

Mutations in the AAAS gene coding for the nuclear pore complex protein ALADIN lead to the autosomal recessive disorder triple A syndrome. Triple A patients present with a characteristic phenotype including alacrima, achalasia and adrenal insufficiency. Patient fibroblasts show increased levels of ox...

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Detalhes bibliográficos
Publicado no:Biol Open
Main Authors: Jühlen, Ramona, Peitzsch, Mirko, Gärtner, Sebastian, Landgraf, Dana, Eisenhofer, Graeme, Huebner, Angela, Koehler, Katrin
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5829508/
https://ncbi.nlm.nih.gov/pubmed/29362278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.030742
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