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Fucosylated Antigens in Cancer: An Alliance toward Tumor Progression, Metastasis, and Resistance to Chemotherapy

Aberrant glycosylation of tumor cells is recognized as a universal hallmark of cancer pathogenesis. Overexpression of fucosylated epitopes, such as type I (H1, Lewis(a), Lewis(b), and sialyl Lewis(a)) and type II (H2, Lewis(x), Lewis(y), and sialyl Lewis(x)) Lewis antigens, frequently occurs on the...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Blanas, Athanasios, Sahasrabudhe, Neha M., Rodríguez, Ernesto, van Kooyk, Yvette, van Vliet, Sandra J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5829055/
https://ncbi.nlm.nih.gov/pubmed/29527514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00039
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