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Modulation of GSK3β autoinhibition by Thr-7 and Thr-8
Glycogen synthase kinase 3β (GSK-3β) is a pivotal signaling node that regulates a myriad of cellular functions and is deregulated in many pathological conditions, making it an attractive therapeutic target. Inhibitory Ser-9 phosphorylation of GSK3β by AKT is an important mechanism for negative regul...
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| Foilsithe in: | FEBS Lett |
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| Main Authors: | , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2018
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5829016/ https://ncbi.nlm.nih.gov/pubmed/29377106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12990 |
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