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Neuroprotective effects of monoacylglycerol lipase inhibitors in experimental ischemic stroke

BACKGROUND AND PURPOSE: Monoacylglycerol lipase (MAGL) is an enzyme that hydrolyzes the endocannabinoid 2-arachidonoylglycerol and regulates production of arachidonic acid and prostaglandins, substances that mediate tissue inflammatory response. Here, we have studied the effects of the selective MAG...

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Detalhes bibliográficos
Publicado no:Stroke
Main Authors: Choi, Sang-Ho, Arai, Allison, Mou, Yongshan, Kang, Byeongteck, Yen, Cecil Chern-Chyi, Hallenbeck, John, Silva, Afonso C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5829008/
https://ncbi.nlm.nih.gov/pubmed/29440474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.117.019664
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