Pharmacokinetics of Dacarbazine (DTIC) in Pregnancy

PURPOSE: The purpose of this report is to describe, for the first time, the pharmacokinetics of dacarbazine (DTIC) and its metabolites (5-[3-methyl-triazen-1-yl]-imidazole-4-carboxamide (MTIC), 5-[3-hydroxymethyl-3-methyl-triazen-1-yl]-imidazole-4-carboxamide (HMMTIC) and 5-aminoimidazole-4-carboxam...

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Bibliographic Details
Published in:Cancer Chemother Pharmacol
Main Authors: Kantrowitz-Gordon, Ira, Hays, Karen, Kayode, Olumide, Kumar, Aditya R., Kaplan, Henry G., Reid, Joel M., Safgren, Stephanie L., Ames, Matthew M., Easterling, Thomas R., Hebert, Mary F.
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828904/
https://ncbi.nlm.nih.gov/pubmed/29305638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-017-3511-6
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