Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy

Diabetic retinopathy is an important cause of blindness in the adult population(1,2) and is characterized by a progressive loss of vascular cells and slow dissolution of inter-vascular junctions resulting in vascular leak and retinal edema(3). Later stages of the disease are characterized by inflamm...

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Published in:Nature
Main Authors: Hu, Jiong, Dziumbla, Sarah, Lin, Jihong, Bibli, Sofia-Iris, Zukunft, Sven, de Mos, Julian, Awwad, Khader, Frömel, Timo, Jungmann, Andreas, Devraj, Kavi, Cheng, Zhixing, Wang, Liya, Fauser, Sascha, Eberhart, Charles G., Sodhi, Akrit, Hammock, Bruce D., Liebner, Stefan, Müller, Oliver J., Glaubitz, Clemens, Hammes, Hans-Peter, Popp, Rüdiger, Fleming, Ingrid
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828869/
https://ncbi.nlm.nih.gov/pubmed/29211719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature25013
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