Ripk3 induces mitochondrial apoptosis via inhibition of FUNDC1 mitophagy in cardiac IR injury

Ripk3-required necroptosis and mitochondria-mediated apoptosis are the predominant types of cell death that largely account for the development of cardiac ischemia reperfusion injury (IRI). Here, we explored the effect of Ripk3 on mitochondrial apoptosis. Compared with wild-type mice, the infarcted...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Zhou, Hao, Zhu, Pingjun, Guo, Jun, Hu, Nan, Wang, Shuyi, Li, Dandan, Hu, Shunying, Ren, Jun, Cao, Feng, Chen, Yundai
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828768/
https://ncbi.nlm.nih.gov/pubmed/28732308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.07.007
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