Ripk3 induces mitochondrial apoptosis via inhibition of FUNDC1 mitophagy in cardiac IR injury

Ripk3-required necroptosis and mitochondria-mediated apoptosis are the predominant types of cell death that largely account for the development of cardiac ischemia reperfusion injury (IRI). Here, we explored the effect of Ripk3 on mitochondrial apoptosis. Compared with wild-type mice, the infarcted...

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Bibliografiska uppgifter
I publikationen:Redox Biol
Huvudupphovsmän: Zhou, Hao, Zhu, Pingjun, Guo, Jun, Hu, Nan, Wang, Shuyi, Li, Dandan, Hu, Shunying, Ren, Jun, Cao, Feng, Chen, Yundai
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2017
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828768/
https://ncbi.nlm.nih.gov/pubmed/28732308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.07.007
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