Epigenetic Changes in the CRH Gene are Related to Severity of Suicide Attempt and a General Psychiatric Risk Score in Adolescents

The aim of this study, comprising 88 suicide attempters, was to identify hypothalamic-pituitary-adrenal (HPA) -axis coupled CpG-sites showing methylation shifts linked to severity of the suicide attempt. Candidate methylation loci were further investigated as risk loci for a general psychiatric risk...

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Publicado en:EBioMedicine
Autores principales: Jokinen, Jussi, Boström, Adrian E., Dadfar, Ali, Ciuculete, Diana M., Chatzittofis, Andreas, Åsberg, Marie, Schiöth, Helgi B.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828554/
https://ncbi.nlm.nih.gov/pubmed/29277323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.12.018
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