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Emerging Players at the Intersection of Chondrocyte Loss of Maturational Arrest, Oxidative Stress, Senescence and Low-Grade Inflammation in Osteoarthritis

The prevalence of Osteoarthritis (OA) is increasing because of the progressive aging and unhealthy lifestyle. These risk factors trigger OA by removing constraints that keep the tightly regulated low turnover of the extracellular matrix (ECM) of articular cartilage, the correct chondrocyte phenotype...

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Publicat a:Oxid Med Cell Longev
Autors principals: Minguzzi, Manuela, Cetrullo, Silvia, D'Adamo, Stefania, Silvestri, Ylenia, Flamigni, Flavio, Borzì, Rosa Maria
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828476/
https://ncbi.nlm.nih.gov/pubmed/29599894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/3075293
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