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Emerging Players at the Intersection of Chondrocyte Loss of Maturational Arrest, Oxidative Stress, Senescence and Low-Grade Inflammation in Osteoarthritis

The prevalence of Osteoarthritis (OA) is increasing because of the progressive aging and unhealthy lifestyle. These risk factors trigger OA by removing constraints that keep the tightly regulated low turnover of the extracellular matrix (ECM) of articular cartilage, the correct chondrocyte phenotype...

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Bibliografiske detaljer
Udgivet i:Oxid Med Cell Longev
Main Authors: Minguzzi, Manuela, Cetrullo, Silvia, D'Adamo, Stefania, Silvestri, Ylenia, Flamigni, Flavio, Borzì, Rosa Maria
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828476/
https://ncbi.nlm.nih.gov/pubmed/29599894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/3075293
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