Emerging Players at the Intersection of Chondrocyte Loss of Maturational Arrest, Oxidative Stress, Senescence and Low-Grade Inflammation in Osteoarthritis

The prevalence of Osteoarthritis (OA) is increasing because of the progressive aging and unhealthy lifestyle. These risk factors trigger OA by removing constraints that keep the tightly regulated low turnover of the extracellular matrix (ECM) of articular cartilage, the correct chondrocyte phenotype...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Minguzzi, Manuela, Cetrullo, Silvia, D'Adamo, Stefania, Silvestri, Ylenia, Flamigni, Flavio, Borzì, Rosa Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828476/
https://ncbi.nlm.nih.gov/pubmed/29599894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/3075293
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