Emerging Players at the Intersection of Chondrocyte Loss of Maturational Arrest, Oxidative Stress, Senescence and Low-Grade Inflammation in Osteoarthritis

The prevalence of Osteoarthritis (OA) is increasing because of the progressive aging and unhealthy lifestyle. These risk factors trigger OA by removing constraints that keep the tightly regulated low turnover of the extracellular matrix (ECM) of articular cartilage, the correct chondrocyte phenotype...

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Dettagli Bibliografici
Pubblicato in:Oxid Med Cell Longev
Autori principali: Minguzzi, Manuela, Cetrullo, Silvia, D'Adamo, Stefania, Silvestri, Ylenia, Flamigni, Flavio, Borzì, Rosa Maria
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2018
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Review Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828476/
https://ncbi.nlm.nih.gov/pubmed/29599894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/3075293
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