Frequency of BRCA1 and BRCA2 causative founder variants in ovarian cancer patients in South-East Poland

BACKGROUND: Causative variants in BRCA1 and BRCA2 are well-established risk factors for breast and ovarian cancer. In Poland, the causative founder variants in the BRCA1 are responsible for a significant proportion of ovarian cancer cases, however, regional differences in the frequencies of various...

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Dades bibliogràfiques
Publicat a:Hered Cancer Clin Pract
Autors principals: Kluz, Tomasz, Jasiewicz, Andrzej, Marczyk, Elżbieta, Jach, Robert, Jakubowska, Anna, Lubiński, Jan, Narod, Steven A., Gronwald, Jacek
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828315/
https://ncbi.nlm.nih.gov/pubmed/29492181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13053-018-0089-x
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