Severe hypoxia selects hematopoietic progenitors with stem cell potential from primary Myelodysplastic syndrome bone marrow cell cultures

Myelodysplastic Syndromes (MDS) are clonal neoplasms where stem/progenitor cells endowed with self-renewal and capable of perpetuating the disease have been demonstrated. It is known that oxygen tension plays a key role in driving normal hematopoiesis and that hematopoietic stem cells are maintained...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Masala, Erico, Valencia-Martinez, Ana, Pillozzi, Serena, Rondelli, Tommaso, Brogi, Alice, Sanna, Alessandro, Gozzini, Antonella, Arcangeli, Annarosa, Sbarba, Persio Dello, Santini, Valeria
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828219/
https://ncbi.nlm.nih.gov/pubmed/29535827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24302
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