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Reduction of microhemorrhages in the spinal cord of symptomatic ALS mice after intravenous human bone marrow stem cell transplantation accompanies repair of the blood-spinal cord barrier

Blood-spinal cord barrier (BSCB) alterations, including capillary rupture, have been demonstrated in animal models of amyotrophic lateral sclerosis (ALS) and ALS patients. To date, treatment to restore BSCB in ALS is underexplored. Here, we evaluated whether intravenous transplantation of human bone...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Eve, David J., Steiner, George, Mahendrasah, Ajay, Sanberg, Paul R., Kurien, Crupa, Thomson, Avery, Borlongan, Cesar V., Garbuzova-Davis, Svitlana
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828209/
https://ncbi.nlm.nih.gov/pubmed/29535831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24360
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