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Between-trial heterogeneity in meta-analyses may be partially explained by reported design characteristics

OBJECTIVE: We investigated the associations between risk of bias judgments from Cochrane reviews for sequence generation, allocation concealment and blinding, and between-trial heterogeneity. STUDY DESIGN AND SETTING: Bayesian hierarchical models were fitted to binary data from 117 meta-analyses, to...

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Bibliographic Details
Published in:J Clin Epidemiol
Main Authors: Rhodes, Kirsty M., Turner, Rebecca M., Savović, Jelena, Jones, Hayley E., Mawdsley, David, Higgins, Julian P.T.
Format: Artigo
Language:Inglês
Published: Elsevier 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828111/
https://ncbi.nlm.nih.gov/pubmed/29217451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jclinepi.2017.11.025
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