Alterations in sperm DNA methylation, non-coding RNA and histone retention associate with DDT-induced epigenetic transgenerational inheritance of disease

BACKGROUND: Environmental toxicants such as DDT have been shown to induce the epigenetic transgenerational inheritance of disease (e.g., obesity) through the germline. The current study was designed to investigate the DDT-induced concurrent alterations of a number of different epigenetic processes i...

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Vydáno v:Epigenetics Chromatin
Hlavní autoři: Skinner, Michael K., Ben Maamar, Millissia, Sadler-Riggleman, Ingrid, Beck, Daniel, Nilsson, Eric, McBirney, Margaux, Klukovich, Rachel, Xie, Yeming, Tang, Chong, Yan, Wei
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827984/
https://ncbi.nlm.nih.gov/pubmed/29482626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-018-0178-0
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