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Ethical issues in pragmatic randomized controlled trials: a review of the recent literature identifies gaps in ethical argumentation

BACKGROUND: Pragmatic randomized controlled trials (RCTs) are designed to evaluate the effectiveness of interventions in real-world clinical conditions. However, these studies raise ethical issues for researchers and regulators. Our objective is to identify a list of key ethical issues in pragmatic...

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Bibliographic Details
Published in:BMC Med Ethics
Main Authors: Goldstein, Cory E., Weijer, Charles, Brehaut, Jamie C., Fergusson, Dean A., Grimshaw, Jeremy M., Horn, Austin R., Taljaard, Monica
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827974/
https://ncbi.nlm.nih.gov/pubmed/29482537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12910-018-0253-x
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