Unravelling the molecular basis for regulatory T‐cell plasticity and loss of function in disease

Regulatory T cells (Treg) are critical for preventing autoimmunity and curtailing responses of conventional effector T cells (Tconv). The reprogramming of T‐cell fate and function to generate Treg requires switching on and off of key gene regulatory networks, which may be initiated by a subtle shift...

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Detalhes bibliográficos
Publicado no:Clin Transl Immunology
Main Authors: Sadlon, Timothy, Brown, Cheryl Y, Bandara, Veronika, Hope, Christopher M, Schjenken, John E, Pederson, Stephen M, Breen, James, Forrest, Alistair, Beyer, Marc, Robertson, Sarah, Barry, Simon C
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Special Feature Reviews
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827651/
https://ncbi.nlm.nih.gov/pubmed/29497530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1011
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