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Dissection of Epitope-Specific Mechanisms of Neutralization of Influenza Virus by Intact IgG and Fab Fragments

The neutralizing antibody (nAb) response against the influenza virus hemagglutinin (HA) fusion glycoprotein is important for preventing viral infection, but we lack a comprehensive understanding of the mechanisms by which these antibodies act. Here we investigated the effect of nAb binding and the r...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Williams, James A., Gui, Long, Hom, Nancy, Mileant, Alexander, Lee, Kelly K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827376/
https://ncbi.nlm.nih.gov/pubmed/29263254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02006-17
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