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Determinants in the Ig Variable Domain of Human HAVCR1 (TIM-1) Are Required To Enhance Hepatitis C Virus Entry

Hepatitis C virus (HCV) is the leading cause of chronic hepatitis in humans. Several host molecules participate in HCV cell entry, but this process remains unclear. The complete unraveling of the HCV entry process is important to further understand viral pathogenesis and develop therapeutics. Human...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Kachko, Alla, Costafreda, Maria Isabel, Zubkova, Iryna, Jacques, Jerome, Takeda, Kazuyo, Wells, Frances, Kaplan, Gerardo, Major, Marian E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827365/
https://ncbi.nlm.nih.gov/pubmed/29321304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01742-17
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