BCR–ABL-specific CD4(+) T-helper cells promote the priming of antigen-specific cytotoxic T cells via dendritic cells

The advent of tyrosine kinase inhibitor (TKI) therapy markedly improved the outcome of patients with chronic-phase chronic myeloid leukemia (CML). However, the poor prognosis of patients with advanced-phase CML and the lifelong dependency on TKIs are remaining challenges; therefore, an effective the...

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Dettagli Bibliografici
Pubblicato in:Cell Mol Immunol
Autori principali: Ueda, Norihiro, Zhang, Rong, Tatsumi, Minako, Liu, Tian-Yi, Kitayama, Shuichi, Yasui, Yutaka, Sugai, Shiori, Iwama, Tatsuaki, Senju, Satoru, Okada, Seiji, Nakatsura, Tetsuya, Kuzushima, Kiyotaka, Kiyoi, Hitoshi, Naoe, Tomoki, Kaneko, Shin, Uemura, Yasushi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827172/
https://ncbi.nlm.nih.gov/pubmed/27181332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2016.7
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