Spatiotemporal regulation of Aurora B recruitment ensures release of cohesion during C. elegans oocyte meiosis

The formation of haploid gametes from diploid germ cells requires the regulated two-step release of sister chromatid cohesion (SCC) during the meiotic divisions. Here, we show that phosphorylation of cohesin subunit REC-8 by Aurora B promotes SCC release at anaphase I onset in C. elegans oocytes. Au...

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Udgivet i:Nat Commun
Main Authors: Ferrandiz, Nuria, Barroso, Consuelo, Telecan, Oana, Shao, Nan, Kim, Hyun-Min, Testori, Sarah, Faull, Peter, Cutillas, Pedro, Snijders, Ambrosius P., Colaiácovo, Monica P., Martinez-Perez, Enrique
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827026/
https://ncbi.nlm.nih.gov/pubmed/29483514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03229-5
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