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Allelic decomposition and exact genotyping of highly polymorphic and structurally variant genes

High-throughput sequencing provides the means to determine the allelic decomposition for any gene of interest—the number of copies and the exact sequence content of each copy of a gene. Although many clinically and functionally important genes are highly polymorphic and have undergone structural alt...

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Publicat a:Nat Commun
Autors principals: Numanagić, Ibrahim, Malikić, Salem, Ford, Michael, Qin, Xiang, Toji, Lorraine, Radovich, Milan, Skaar, Todd C., Pratt, Victoria M., Berger, Bonnie, Scherer, Steve, Sahinalp, S. Cenk
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826927/
https://ncbi.nlm.nih.gov/pubmed/29483503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03273-1
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