Leishmania guyanensis parasites block the activation of the inflammasome by inhibiting maturation of IL-1β

The various symptomatic outcomes of cutaneous leishmaniasis relates to the type and potency of its underlying inflammatory responses. Presence of the cytoplasmic Leishmania RNA virus-1 (LRV1) within Leishmania guyanensis, worsens lesional inflammation and parasite burden, as the viral dsRNA genome a...

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Bibliografiske detaljer
Udgivet i:Microb Cell
Main Authors: Hartley, Mary-Anne, Eren, Remzi O., Rossi, Matteo, Prevel, Florence, Castiglioni, Patrik, Isorce, Nathalie, Desponds, Chantal, Lye, Lon-Fye, Beverley, Stephen M., Drexler, Stefan K., Fasel, Nicolas
Format: Artigo
Sprog:Inglês
Udgivet: Shared Science Publishers OG 2018
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826701/
https://ncbi.nlm.nih.gov/pubmed/29487860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/mic2018.03.619
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