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Sepsis induced T cell immunoparalysis: the ins and outs of impaired T cell immunity()

Sepsis results in a deluge of both pro- and anti-inflammatory cytokines leading to lymphopenia and chronic immunoparalysis. Sepsis induced long-lasting immunoparalysis is, in part, defined by impaired CD4 and CD8 αβ T cell responses in the post-septic environment. The dysfunction in T cell immunity...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Jensen, Isaac J, Sjaastad, Frances V, Griffith, Thomas S, Badovinac, Vladimir P
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826615/
https://ncbi.nlm.nih.gov/pubmed/29463691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701618
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