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Regulation of STAT3 and NF-κB Activations by S-Nitrosylation in Multiple Myeloma

Numerous reports suggest that aberrant activations of STAT3 and NF-κB promote survival and proliferation of multiple myeloma (MM) cells. In the present report, we demonstrate that a synthetic S-nitrosothiol compound, S-nitroso-N-acetylcysteine (SNAC), inhibits proliferation and survival of multiple...

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Detalhes bibliográficos
Publicado no:Free Radic Biol Med
Main Authors: Kim, Jinsu, Choi, Seungho, Saxena, Nishant, Singh, Avtar K., Singh, Inderjit, Won, Je-Seong
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826580/
https://ncbi.nlm.nih.gov/pubmed/28232202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2017.02.039
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