Uncovering the Signaling Pathway behind Extracellular Guanine-Induced Activation of NO System: New Perspectives in Memory-Related Disorders

Mounting evidence suggests that the guanine-based purines stand out as key player in cell metabolism and in several models of neurodegenerative disorders, such as Parkinson’s and Alzheimer’s diseases. Guanosine (GUO) and guanine (GUA) are extracellular signaling molecules derived from the breakdown...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Zuccarini, Mariachiara, Giuliani, Patricia, Frinchi, Monica, Mudò, Giuseppa, Serio, Rosa Maria, Belluardo, Natale, Buccella, Silvana, Carluccio, Marzia, Condorelli, Daniele F., Caciagli, Francesco, Ciccarelli, Renata, Di Iorio, Patrizia
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826394/
https://ncbi.nlm.nih.gov/pubmed/29515443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00110
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