The Expression and Prognostic Impact of Immune Cytolytic Activity-Related Markers in Human Malignancies: A Comprehensive Meta-analysis

BACKGROUND: Recently, immune-checkpoint blockade has shown striking clinical results in different cancer patients. However, a significant inter-individual and inter-tumor variability exists among different cancers. The expression of the toxins granzyme A (GZMA) and perforin 1 (PRF1), secreted by eff...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Roufas, Constantinos, Chasiotis, Dimitrios, Makris, Anestis, Efstathiades, Christodoulos, Dimopoulos, Christos, Zaravinos, Apostolos
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826382/
https://ncbi.nlm.nih.gov/pubmed/29515971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00027
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