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Coevolution of the Toll-Like Receptor 4 Complex with Calgranulins and Lipopolysaccharide

Toll-like receptor 4 (TLR4) induces inflammation in response to both pathogen- and host-derived molecules. Lipopolysaccharide (LPS) recognition by TLR4 has been shown to occur across the amniotes, but endogenous signaling through TLR4 has not been validated outside of placental mammals. To determine...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Loes, Andrea N., Bridgham, Jamie T., Harms, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826337/
https://ncbi.nlm.nih.gov/pubmed/29515592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00304
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