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Dupilumab: an evidence-based review of its potential in the treatment of atopic dermatitis

INTRODUCTION: Atopic dermatitis (AD) is a recurrent, pruritic inflammatory skin disease with complex immunopathogenesis characterized by a dominant T(H)2 response. Dupilumab is an interleukin (IL)-4 receptor alpha antagonist that subsequently blocks IL-4 and IL-13 signaling. It has recently been app...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Core Evid
Hauptverfasser: Eshtiaghi, Panteha, Gooderham, Melinda J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826246/
https://ncbi.nlm.nih.gov/pubmed/29503598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CE.S133661
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