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Targeting Fibroblast Growth Factor 23 Signaling with Antibodies and Inhibitors, Is There a Rationale?

Fibroblast growth factor 23 (FGF23) is a phosphotropic hormone mainly produced by bone. FGF23 reduces serum phosphate by suppressing intestinal phosphate absorption through reducing 1,25-dihydroxyvitamin D and proximal tubular phosphate reabsorption. Excessive actions of FG23 result in several kinds...

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Vydáno v:Front Endocrinol (Lausanne)
Hlavní autor: Fukumoto, Seiji
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826173/
https://ncbi.nlm.nih.gov/pubmed/29515522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2018.00048
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