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Single-Dose Pharmacokinetics and Safety of Meropenem-Vaborbactam in Subjects with Chronic Renal Impairment

Vaborbactam is a member of a new class of β-lactamase inhibitors with inhibitory activity against serine carbapenemases (e.g., Klebsiella pneumoniae carbapenemase) that has been developed in combination with meropenem. The pharmacokinetics of the combination was evaluated in 41 subjects with chronic...

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Publicado en:Antimicrob Agents Chemother
Main Authors: Rubino, Christopher M., Bhavnani, Sujata M., Loutit, Jeffery S., Lohse, Brooke, Dudley, Michael N., Griffith, David C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826113/
https://ncbi.nlm.nih.gov/pubmed/29311069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02103-17
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