Role of 11β-HSD type 1 in abnormal HPA axis activity during immune-mediated arthritis

Patients with chronic immune-mediated arthritis exhibit abnormal hypothalamo-pituitary-adrenal (HPA) axis activity. The basis for this abnormality is not known. Immune-mediated arthritis is associated with increased extra-adrenal synthesis of active glucocorticoids by the 11β-hydroxysteroid dehydrog...

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Detalhes bibliográficos
Publicado no:Endocr Connect
Main Authors: Sattler, Janko, Tu, Jinwen, Stoner, Shihani, Li, Jingbao, Buttgereit, Frank, Seibel, Markus J, Zhou, Hong, Cooper, Mark S
Formato: Artigo
Idioma:Inglês
Publicado em: Bioscientifica Ltd 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5825927/
https://ncbi.nlm.nih.gov/pubmed/29386227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EC-17-0361
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