Autophagy Mediates Interleukin-1β Secretion in Human Neutrophils

Interleukin-1β (IL-1β), a major pro-inflammatory cytokine, is a leaderless cytosolic protein whose secretion does not follow the classical endoplasmic reticulum-to-Golgi pathway, and for which a canonical mechanism of secretion remains to be established. Neutrophils are essential players against bac...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Iula, Leonardo, Keitelman, Irene A., Sabbione, Florencia, Fuentes, Federico, Guzman, Mauricio, Galletti, Jeremías Gastón, Gerber, Pehuén Pereyra, Ostrowski, Matías, Geffner, Jorge R., Jancic, Carolina C., Trevani, Analía S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5825906/
https://ncbi.nlm.nih.gov/pubmed/29515581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00269
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