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A branching morphogenesis program governs embryonic growth of the thyroid gland

The developmental program that regulates thyroid progenitor cell proliferation is largely unknown. Here, we show that branching-like morphogenesis is a driving force to attain final size of the embryonic thyroid gland in mice. Sox9, a key factor in branching organ development, distinguishes Nkx2-1(+...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Liang, Shawn, Johansson, Ellen, Barila, Guillermo, Altschuler, Daniel L., Fagman, Henrik, Nilsson, Mikael
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5825846/
https://ncbi.nlm.nih.gov/pubmed/29361553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.146829
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