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Estrogen‐dependent control and cell‐to‐cell variability of transcriptional bursting

Cellular decision‐making and environmental adaptation are dependent upon a heterogeneous response of gene expression to external cues. Heterogeneity arises in transcription from random switching between transcriptionally active and inactive states, resulting in bursts of RNA synthesis. Furthermore,...

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Bibliografiske detaljer
Udgivet i:Mol Syst Biol
Main Authors: Fritzsch, Christoph, Baumgärtner, Stephan, Kuban, Monika, Steinshorn, Daria, Reid, George, Legewie, Stefan
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5825209/
https://ncbi.nlm.nih.gov/pubmed/29476006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20177678
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