GM1 ganglioside-independent intoxication by Cholera toxin

Cholera toxin (CT) enters and intoxicates host cells after binding cell surface receptors via its B subunit (CTB). We have recently shown that in addition to the previously described binding partner ganglioside GM1, CTB binds to fucosylated proteins. Using flow cytometric analysis of primary human j...

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Pubblicato in:PLoS Pathog
Autori principali: Cervin, Jakob, Wands, Amberlyn M., Casselbrant, Anna, Wu, Han, Krishnamurthy, Soumya, Cvjetkovic, Aleksander, Estelius, Johanna, Dedic, Benjamin, Sethi, Anirudh, Wallom, Kerri-Lee, Riise, Rebecca, Bäckström, Malin, Wallenius, Ville, Platt, Frances M., Lebens, Michael, Teneberg, Susann, Fändriks, Lars, Kohler, Jennifer J., Yrlid, Ulf
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5825173/
https://ncbi.nlm.nih.gov/pubmed/29432456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006862
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