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Same but not alike: Structure, flexibility and energetics of domains in multi-domain proteins are influenced by the presence of other domains

The majority of the proteins encoded in the genomes of eukaryotes contain more than one domain. Reasons for high prevalence of multi-domain proteins in various organisms have been attributed to higher stability and functional and folding advantages over single-domain proteins. Despite these advantag...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Vishwanath, Sneha, de Brevern, Alexandre G., Srinivasan, Narayanaswamy
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5825166/
https://ncbi.nlm.nih.gov/pubmed/29432415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006008
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