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Heritable tumor cell division rate heterogeneity induces clonal dominance
Tumors consist of a hierarchical population of cells that differ in their phenotype and genotype. This hierarchical organization of cells means that a few clones (i.e., cells and several generations of offspring) are abundant while most are rare, which is called clonal dominance. Such dominance also...
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| Publicado no: | PLoS Comput Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5825147/ https://ncbi.nlm.nih.gov/pubmed/29432417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005954 |
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