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Phenyl sulfate, indoxyl sulfate and p-cresyl sulfate decrease glutathione level to render cells vulnerable to oxidative stress in renal tubular cells

In chronic kidney disease patients, oxidative stress is generally associated with disease progression and pathogenesis of its comorbidities. Phenyl sulfate is a protein-bound uremic solute, which accumulates in chronic kidney disease patients, but little is known about its nature. Although many repo...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Edamatsu, Takeo, Fujieda, Ayako, Itoh, Yoshiharu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5825083/
https://ncbi.nlm.nih.gov/pubmed/29474405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193342
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