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Circulating extracellular DNA is an independent predictor of mortality in elderly patients with venous thromboembolism

BACKGROUND: Venous thromboembolism (VTE) is a major cause of morbidity and mortality in elderly patients. Extracellular DNA is a pro-inflammatory and pro-thrombotic mediator in vitro and in animal models. Levels of circulating extracellular DNA (ceDNA) are increased in VTE patients, but the associat...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Jiménez-Alcázar, Miguel, Limacher, Andreas, Panda, Rachita, Méan, Marie, Bitterling, Josephine, Peine, Sven, Renné, Thomas, Beer, Jürg H., Aujesky, Drahomir, Lämmle, Bernhard, Fuchs, Tobias A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5825008/
https://ncbi.nlm.nih.gov/pubmed/29474368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191150
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