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CR6 interacting factor 1 deficiency promotes endothelial inflammation by SIRT1 downregulation
AIMS: CR6 interacting factor 1 (CRIF1) deficiency impairs mitochondrial oxidative phosphorylation complexes, contributing to increased mitochondrial and cellular reactive oxygen species (ROS) production. CRIF1 downregulation has also been revealed to decrease sirtuin 1 (SIRT1) expression and impair...
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| Veröffentlicht in: | PLoS One |
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5825004/ https://ncbi.nlm.nih.gov/pubmed/29474366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0192693 |
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