Randomized, controlled trial of TNF-α antagonist in CTL-mediated severe cutaneous adverse reactions

BACKGROUND. Cytotoxic T lymphocyte–mediated (CTL-mediated) severe cutaneous adverse reactions (SCARs), including Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), are rare but life-threatening adverse reactions commonly induced by drugs. Although high levels of CTL-associated cyto...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Wang, Chuang-Wei, Yang, Lan-Yan, Chen, Chun-Bing, Ho, Hsin-Chun, Hung, Shuen-Iu, Yang, Chih-Hsun, Chang, Chee-Jen, Su, Shih-Chi, Hui, Rosaline Chung-Yee, Chin, See-Wen, Huang, Li-Fang, Lin, Yang Yu-Wei, Chang, Wei-Yang, Fan, Wen-Lang, Yang, Chin-Yi, Ho, Ji-Chen, Chang, Ya-Ching, Lu, Chun-Wei, Chung, Wen-Hung
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Clinical Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824923/
https://ncbi.nlm.nih.gov/pubmed/29400697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI93349
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