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Radiosynthesis and evaluation of an (18)F–labeled silicon containing exendin-4 peptide as a PET probe for imaging insulinoma
BACKGROUND: Analogues of exendin-4 have been radiolabeled for imaging the glucagon-like peptide type 1 receptors (GLP-1R) which are overexpressed in insulinoma. The aim of this research was to synthesize an (18)F–labeled silicon containing exendin-4 peptide ((18)F-2) and to evaluate its in vitro and...
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| Veröffentlicht in: | EJNMMI Radiopharm Chem |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer International Publishing
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5824708/ https://ncbi.nlm.nih.gov/pubmed/29503858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41181-017-0036-6 |
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