Radiosynthesis and evaluation of an (18)F–labeled silicon containing exendin-4 peptide as a PET probe for imaging insulinoma

BACKGROUND: Analogues of exendin-4 have been radiolabeled for imaging the glucagon-like peptide type 1 receptors (GLP-1R) which are overexpressed in insulinoma. The aim of this research was to synthesize an (18)F–labeled silicon containing exendin-4 peptide ((18)F-2) and to evaluate its in vitro and...

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Bibliografiske detaljer
Udgivet i:EJNMMI Radiopharm Chem
Main Authors: Dialer, Lukas O., Jodal, Andreas, Schibli, Roger, Ametamey, Simon M., Béhé, Martin
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824708/
https://ncbi.nlm.nih.gov/pubmed/29503858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41181-017-0036-6
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