5-Fluorouracil chemotherapy upregulates cytokines and alters hippocampal dendritic complexity in aged mice

5-fluorouracil (5-Fu) is commonly used chemotherapy drug, but it can lead to the impairment of cognitive function. The pathogenesis of this injury is unknown but may involve modifications to dendritic structure and/or alterations in dendritic spine density and morphology. Dendritic spines are sites...

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Gepubliceerd in:Behav Brain Res
Hoofdauteurs: Groves, Thomas R., Farris, Ryan, Anderson, Julie E., Alexander, Tyler C., Kiffer, Frederico, Carter, Gwendolyn, Wang, Jing, Boerma, Marjan, Allen, Antiño R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824640/
https://ncbi.nlm.nih.gov/pubmed/27599618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2016.08.039
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