Metronomic Chemotherapy vs Best Supportive Care in Progressive Pediatric Solid Malignant Tumors: A Randomized Clinical Trial

IMPORTANCE: Although oral metronomic chemotherapy is often used in progressive pediatric solid malignant tumors, a literature review reveals that only small single-arm retrospective or phase 1 and 2 studies have been performed. Skepticism abounds because of the lack of level 1 evidence. OBJECTIVES:...

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Detalhes bibliográficos
Publicado no:JAMA Oncol
Main Authors: Pramanik, Raja, Agarwala, Sandeep, Gupta, Yogendra Kumar, Thulkar, Sanjay, Vishnubhatla, Sreenivas, Batra, Atul, Dhawan, Deepa, Bakhshi, Sameer
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2017
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824286/
https://ncbi.nlm.nih.gov/pubmed/28384657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2017.0324
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