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False-Positive Xpert MTB/RIF Results in Retested Patients with Previous Tuberculosis: Frequency, Profile, and Prospective Clinical Outcomes

Globally, Xpert MTB/RIF (Xpert) is the most widely used PCR test for the diagnosis of tuberculosis (TB). Positive results in previously treated patients, which are due to old DNA or active disease, are a diagnostic dilemma. We prospectively retested sputum from 238 patients, irrespective of current...

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Détails bibliographiques
Publié dans:J Clin Microbiol
Auteurs principaux: Theron, Grant, Venter, Rouxjeane, Smith, Liezel, Esmail, Aliasgar, Randall, Philippa, Sood, Vishesh, Oelfese, Suzette, Calligaro, Greg, Warren, Robin, Dheda, Keertan
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824043/
https://ncbi.nlm.nih.gov/pubmed/29305538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01696-17
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