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Transcription Factor Target Gene Network governs the Logical Abstraction Analysis of the Synthetic Circuit in Leishmaniasis

With the advent of synthetic biology in medicine many synthetic or engineered proteins have made their way to therapeutics and diagnostics. In this paper, the downstream gene network of CD14-TNF-EGFR pathway in leishmaniasis, a tropical disease, is reconstructed. Network analysis showed that NFkB li...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Mol, Milsee, Kosey, Dipali, Boppana, Ramanamurthy, Singh, Shailza
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823942/
https://ncbi.nlm.nih.gov/pubmed/29472639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21840-w
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