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Early sclerostin expression explains bone formation inhibition before arthritis onset in the rat adjuvant-induced arthritis model

Periarticular bone loss in rheumatoid arthritis (RA) is considered to be mainly related to synovial inflammation. However, strong bone loss has also described at the time of arthritis onset. Recently, a paradoxical exacerbation of joint damage was described when blocking sclerostin in various arthri...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Courbon, Guillaume, Lamarque, Raphaëlle, Gerbaix, Maude, Caire, Robin, Linossier, Marie-Thérèse, Laroche, Norbert, Thomas, Mireille, Thomas, Thierry, Vico, Laurence, Marotte, Hubert
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823923/
https://ncbi.nlm.nih.gov/pubmed/29472591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21886-w
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