Citalopram inhibits platelet function independently of SERT-mediated 5-HT transport

Citalopram prevents serotonin (5-HT) uptake into platelets by blocking the serotonin reuptake transporter (SERT). Although some clinical data suggest that selective serotonin reuptake inhibitors (SSRIs) may affect haemostasis and thrombosis, these poorly-characterised effects are not well understood...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Roweth, Harvey G., Yan, Ruoling, Bedwani, Nader H., Chauhan, Alisha, Fowler, Nicole, Watson, Alice H., Malcor, Jean-Daniel, Sage, Stewart O., Jarvis, Gavin E.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823918/
https://ncbi.nlm.nih.gov/pubmed/29472624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21348-3
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